Cisco ISR 4221 / 4321 / 4331 / 4351 / 4431 / 4451 End of Life & EOSL Date

OEM supported

The Cisco ISR 4221 / 4321 / 4331 / 4351 / 4431 / 4451 reaches End of Service Life (EOSL) on 30 Nov 2028.

End of sale
07 Nov 2023

EOSL
30 Nov 2028

Manufacturer: Cisco
Product family: ISR
Models / part numbers: ISR4221/K9, ISR4321/K9, ISR4331/K9, ISR4351/K9, ISR4431/K9, ISR4451-X/K9
Category: Router
End of sale / EOL: 07 Nov 2023
End of Service Life: 30 Nov 2028
Source: OEM end-of-life notice · view source
Notes: Replacement: Catalyst 8200 / 8300.
Last checked: 13 Nov 2026

Frequently asked questions

When is the Cisco ISR 4221 / 4321 / 4331 / 4351 / 4431 / 4451 End of Service Life?

Cisco ISR 4221 / 4321 / 4331 / 4351 / 4431 / 4451 reaches End of Service Life on 30 Nov 2028, after End of Sale on 07 Nov 2023.

What happens after the ISR 4221 / 4321 / 4331 / 4351 / 4431 / 4451 reaches EOSL?

Cisco stops selling support contracts, spare parts and firmware updates. The hardware keeps working, but break/fix, parts and engineering help must come from a third-party maintenance provider.

Can SLA Expert support the ISR 4221 / 4321 / 4331 / 4351 / 4431 / 4451 after EOSL?

Yes — SLA Expert provides multi-vendor third-party maintenance, spares and field engineering for post-EOSL Cisco equipment across the Middle East and Africa. Request a quote to confirm coverage for your units.

Related Cisco EOSL dates

Model	Category	End of sale	EOSL date	Status
ISR 4461 ISR4461/K9	Router	—	31 Jan 2030	OEM supported
ISR G2 2900 / 3900 Series CISCO2901/K9, CISCO2911/K9, CISCO2921/K9, CISCO2951/K9, CISCO3925/K9, CISCO3945/K9	Router	—	31 Dec 2022	Past EOSL
ISR G2 1921 / 1941 CISCO1921/K9, CISCO1941/K9	Router	—	30 Sep 2023	Past EOSL
ASA 5520 / 5540 / 5550 ASA5520, ASA5540, ASA5550	Firewall	—	30 Sep 2018	Past EOSL
Catalyst 4500 Supervisor 6-E WS-X45-SUP6-E	Network Module	01 Mar 2014	28 Feb 2019	Past EOSL
Nexus 7000 Supervisor 1 N7K-SUP1	Network Module	15 Aug 2014	31 Aug 2019	Past EOSL